Spray Drying with LEWA Pumps

Solutions

Advantages of LEWA diaphragm metering pumps for pharmaceutical spray dryers:

Hermetically sealed, no contaminants can get in or out
Easy-to-clean design, easy accessibility for maintenance purposes
High security thanks to 4-layer sandwich diaphragm with diaphragm monitoring and signaling without product contamination
Clean operation – no particle abrasion in the LEWA pump
Hygienic design, specially developed with and for the pharmaceutical industry (GMP-compliant)
Coating of spray dryer nozzles with constant pressure through a rigid pump curve
Gentle conveyance, no high shear forces
Low hold-up in the pump head thanks to design with minimized dead space
CIP; SIP; DIP
FAT, SAT and global service

Options:

Material 1.4435 (AISI 316L) with a surface roughness of Ra < 0.5µm
Inert and FDA compliant construction materials
Ex-proof protection, ATEX conformity
According to ASME BPE
Comprehensive documentation for qualification

LEWA is a member of leading committees for the hygienic design of pumps and systems.

QHD Certificate

Areas of application

LEWA metering pumps are used, for example, for:

Aqueous solutions, suspensions and emulsions
Compositions based on organic solvents, such as ethanol, isopropanol, acetone or methylene chloride

Filler, binder, disintegrants, sliding agents can thus be dissolved or suspended and transferred with the active material in defined, dry, free flowing, uniform particles.

Background

The fundamental concept of spray drying

The production of finely dispersed powder from a wet charging fluid by vaporizing the liquid:

A solution /suspension is sprayed via nozzles or rotating disk atomizers into a hot air or nitrogen flow
The supply to the spray drying system uses suitable pumps. Drying and particle formation are done simultaneously in the spraying process during this process. Due to these higher requirements on the pharmaceutical technology, the demands which are put on the bioavailability of a drug also increase. The effectiveness of a drug also depends on the generated particle size, after all.

Important customer requirements for this are:

Particle size distribution
Percentage of residual moisture
Bulk density and particle shape
Maintaining exact and consistent quality standards
Precise, continuing, safe and
low-pulsation fluid supply

Process scheme pharmaceutical spray drying

Industries

Pumps specially designed for the Cosmetics Industry

Personal care

LEWA is your reliable partner in the production of personal care products. Our systems meet the strictest quality and hygiene requirements. Ask us for more information!

LEWA pumps and systems meet the requirements of the Pharmaceuticals industry

Pharma, Life Science & Biotech

LEWA supplies pumps and systems for the pharmaceutical, life sciences, and biotech industries that comply with all hygienic requirements. We're happy to help you!